

Postoperative fever: A Practical Guide to Assessment and Management
Postoperative fever, especially in the first few days after surgery, is often benign and does not require the same aggressive approach. Multiple studies indicate that it is frequently over-investigated and over-treated. This blog post attempts to give guidance on how to deal with postoperative fever.
4 days ago5 min read


A critical look at the debate around contact precautions for MRSA carriers
This blog aims to provide a more nuanced analysis of the pro/con debate in the New England Journal of Medicine (NEJM) on whether to continue contact precautions for MRSA carriers.
Jan 256 min read


Beta-Lactam Treatment Options for Carbapenem-Resistant Organisms: A Practical Guide
Antimicrobial resistance poses a growing global threat to public health, directly causing an estimated 1.27 million deaths in 2019 alone (1). In clinical practice, this rise in resistance means clinicians will increasingly encounter infections where carbapenems - the once, reliable last-line agents - are ineffective. Since resistance mechanisms can often be determined before susceptibility results are available, this blog provides a schematic overview of beta-lactam treatment
Jan 73 min read


Is piperacillin-tazobactam still a valid option for treating infections by ESBL-producing bacteria?
1. What was the impact of the MERINO study on treatment approaches of ESBL-producing infections?
2. Why MERINO study’s intrinsic flaws may invalidate its conclusions?
3. How to deal with the results from the MERINO study?
Dec 18, 20257 min read


Influenza treatment - anything to add?
1. What is the role of corticosteroids in treating influenza?
2. Should antibiotics - particularly macrolides - be used for severe influenza infections?
3. What evidence exists for other therapies in influenza-related ARDS
Dec 4, 20256 min read


Initiating antibiotics in sepsis: when late becomes too late
New retrospective studies continue to claim that each hour delay in antibiotic administration significantly increases mortality in sepsis and septic shock, implying that any patient with a hint of sepsis should receive antibiotics immediately. However, both sepsis and septic shock can present with widely variable clinical features, making diagnosis challenging. This blog explores the current evidence regarding the time to antibiotic administration in sepsis and septic shock.
Nov 24, 202510 min read


Are Echinocandins superior to Triazoles for the treatment of invasive candidiasis?
Who are ‘the good, bad and ugly’ in the echinocandins versus triazoles discussion?
Oct 29, 20257 min read

